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Harry Schachter Selected Research

UDP-GlcNAc alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase

12/2002The role of the GlcNAc(beta)1,2Man(alpha)- moiety in mammalian development. Null mutations of the genes encoding UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2 cause embryonic lethality and congenital muscular dystrophy in mice and men, respectively.

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Harry Schachter Research Topics

Disease

9Muscular Dystrophies (Muscular Dystrophy)
01/2010 - 12/2002
8Walker-Warburg Syndrome
05/2012 - 12/2002
5Neoplasms (Cancer)
01/2017 - 01/2002
3Neoplasm Metastasis (Metastasis)
01/2012 - 01/2002
3Eye Abnormalities (Eye Abnormality)
08/2008 - 07/2003
2Inflammation (Inflammations)
10/2005 - 01/2002
1Prostatic Neoplasms (Prostate Cancer)
08/2008
1Myopia
01/2008
1Intellectual Disability (Idiocy)
01/2008
1Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy)
01/2008
1Cobblestone Lissencephaly
08/2006
1Hydrocephalus (Hydrocephaly)
08/2006
1Infections
10/2004
1Congenital disorder of glycosylation type 2A
12/2002

Drug/Important Bio-Agent (IBA)

7Dystroglycans (Dystroglycan)IBA
05/2012 - 07/2003
6Polysaccharides (Glycans)IBA
01/2017 - 12/2002
5Proteins (Proteins, Gene)FDA Link
01/2010 - 12/2002
3EnzymesIBA
01/2012 - 02/2006
2Laminin (Merosin)IBA
01/2010 - 07/2004
2protein O-mannose beta-1,2-N-acetylglucosaminyltransferaseIBA
01/2008 - 07/2003
2CarbohydratesIBA
10/2005 - 01/2002
2GlycosyltransferasesIBA
07/2004 - 01/2004
2AcetylglucosamineIBA
12/2002 - 12/2002
2MannosidesIBA
12/2002 - 12/2002
2Uridine Diphosphate (UDP)IBA
12/2002 - 12/2002
1Glycoproteins (Glycoprotein)IBA
01/2017
1Growth Factor ReceptorsIBA
01/2017
1Small Interfering RNA (siRNA)IBA
01/2012
1Mannose (D-Mannose)IBA
01/2010
1Digoxin (Digitek)FDA LinkGeneric
08/2008
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
10/2005
1Bacterial ToxinsIBA
10/2004
1Proteoglycans (Proteoglycan)IBA
10/2004
1OligosaccharidesIBA
01/2004
1Indicators and Reagents (Reagents)IBA
07/2003
1LigandsIBA
07/2003
1UDP-GlcNAc alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferaseIBA
12/2002

Therapy/Procedure

1Therapeutics
01/2012